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Patrício Soares-da-Silva Selected Research

Seizures (Absence Seizure)

10/2021Safety of Eslicarbazepine Acetate in Elderly Versus Non-Elderly Patients with Focal Seizures: From Pooled Data of Clinical Studies to 8 Years of Post-Marketing Experience.
5/2020Analysis of cutaneous allergic reactions in clinical trials of eslicarbazepine acetate.
1/2020Efficacy and safety of eslicarbazepine acetate as adjunctive therapy for refractory focal-onset seizures in children: A double-blind, randomized, placebo-controlled, parallel-group, multicenter, phase-III clinical trial.
12/2018Safety, Tolerability and Efficacy of Eslicarbazepine Acetate as Adjunctive Therapy in Patients Aged ≥ 65 Years with Focal Seizures.
1/2018Efficacy and safety of eslicarbazepine acetate versus controlled-release carbamazepine monotherapy in newly diagnosed epilepsy: A phase III double-blind, randomized, parallel-group, multicenter study.
12/2017Safety Profile of Eslicarbazepine Acetate as Add-On Therapy in Adults with Refractory Focal-Onset Seizures: From Clinical Studies to 6 Years of Post-Marketing Experience.
12/2017Pooled efficacy and safety of eslicarbazepine acetate as add-on treatment in patients with focal-onset seizures: Data from four double-blind placebo-controlled pivotal phase III clinical studies.
10/2015Carbamazepine aggravates absence seizures in two dedicated mouse models.
3/2015Assessment of the efficacy and safety of eslicarbazepine acetate in acute mania and prevention of recurrence: experience from multicentre, double-blind, randomised phase II clinical studies in patients with bipolar disorder I.
3/2015Eslicarbazepine acetate for the treatment of focal epilepsy: an update on its proposed mechanisms of action.
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Patrício Soares-da-Silva Research Topics

Disease

34Parkinson Disease (Parkinson's Disease)
09/2022 - 06/2003
18Seizures (Absence Seizure)
10/2021 - 12/2004
13Hypertension (High Blood Pressure)
07/2021 - 01/2002
12Epilepsy (Aura)
01/2021 - 12/2004
6Heart Failure
01/2019 - 03/2002
5Dyskinesias (Dyskinesia)
01/2020 - 01/2007
4Partial Epilepsies (Epilepsy, Partial)
10/2020 - 03/2007
4Body Weight (Weight, Body)
10/2019 - 10/2015
3Nervous System Diseases (Neurological Disorders)
10/2020 - 01/2007
3Bipolar Disorder (Manic Depressive Psychosis)
03/2015 - 01/2007
3Essential Hypertension
10/2014 - 01/2004
2Pain (Aches)
03/2022 - 10/2018
2Cardiomegaly (Heart Hypertrophy)
07/2021 - 01/2019
2Unconsciousness (Loss of Consciousness)
05/2020 - 10/2019
2Hypersensitivity (Allergy)
05/2020 - 05/2008
2Neuroblastoma
03/2019 - 02/2015
2Inflammation (Inflammations)
01/2019 - 04/2016
2Sleep Initiation and Maintenance Disorders (Insomnia)
01/2019 - 01/2016
2Constipation
01/2019 - 01/2016
2Breast Neoplasms (Breast Cancer)
05/2018 - 12/2017
2Temporal Lobe Epilepsy
01/2018 - 02/2014
2Diarrhea
10/2017 - 01/2016
2Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
10/2017 - 10/2015
1Dizziness (Lightheadedness)
10/2021
1Tremor (Tremors)
02/2021
1Stroke (Strokes)
01/2020
1Frailty
10/2019
1Adenocarcinoma
03/2019
1Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2019
1Cardiovascular Diseases (Cardiovascular Disease)
01/2019
1Pulmonary Arterial Hypertension
05/2018
1Drug-Related Side Effects and Adverse Reactions
12/2017
1Hyponatremia
12/2017
1Porcine Reproductive and Respiratory Syndrome (PRRS)
10/2017
1Mania (Manias)
03/2015
1Tachycardia (Tachyarrhythmias)
01/2015
1Peripheral Nervous System Diseases (PNS Diseases)
11/2014
1Schizophrenia (Dementia Praecox)
11/2014

Drug/Important Bio-Agent (IBA)

27Levodopa (L Dopa)FDA LinkGeneric
09/2022 - 06/2003
23eslicarbazepine acetateIBA
10/2021 - 08/2004
21opicaponeIBA
09/2022 - 01/2012
14Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA
02/2021 - 11/2003
10Dopamine (Intropin)FDA LinkGeneric
10/2020 - 01/2002
10Anticonvulsants (Antiepileptic Drugs)IBA
12/2017 - 12/2004
8Carbamazepine (Tegretol)FDA LinkGeneric
10/2020 - 12/2004
7SodiumIBA
10/2017 - 03/2002
5nebicaponeIBA
01/2012 - 06/2003
4Pharmaceutical PreparationsIBA
10/2021 - 01/2010
4SaltsIBA
07/2021 - 01/2004
4eslicarbazepineIBA
03/2015 - 02/2014
3zamicastatIBA
10/2019 - 05/2018
3entacapone (Comtan)FDA Link
01/2016 - 01/2008
3Voltage-Gated Sodium ChannelsIBA
03/2015 - 01/2007
3Amino Acid Transport Systems (Amino Acid Transporter)IBA
08/2013 - 12/2007
2BenserazideIBA
02/2021 - 12/2010
2Propofol (Diprivan)FDA LinkGeneric
05/2020 - 10/2019
2Tolcapone (Tasmar)FDA Link
03/2019 - 01/2016
2Norepinephrine (Noradrenaline)FDA LinkGeneric
01/2019 - 05/2018
2Member 1 Subfamily B ATP Binding Cassette TransporterIBA
05/2018 - 12/2017
2Proteins (Proteins, Gene)FDA Link
05/2018 - 12/2017
2Mixed Function Oxygenases (Monooxygenases)IBA
05/2018 - 01/2015
2etamicastatIBA
05/2018 - 01/2015
2Sodium Channels (Sodium Channel)IBA
01/2018 - 02/2015
210,11- dihydro- 10- hydroxy- 5H- dibenz(b,f)azepine- 5- carboxamideIBA
01/2018 - 02/2014
2Pattern Recognition ReceptorsIBA
10/2017 - 10/2015
2Adenosine Triphosphatases (ATPase)IBA
01/2016 - 12/2007
2Sodium-Hydrogen ExchangersIBA
01/2016 - 12/2007
2Biological ProductsIBA
11/2014 - 12/2004
2Oxcarbazepine (Trileptal)FDA LinkGeneric
08/2010 - 12/2004
1Dopa DecarboxylaseIBA
03/2022
1Protein Isoforms (Isoforms)IBA
07/2021
13-methoxytyrosineIBA
02/2021
11- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
02/2021
1nitrocatecholIBA
02/2021
1BIA 10-2474IBA
01/2020
1Biomarkers (Surrogate Marker)IBA
01/2019
1fatty-acid amide hydrolase (fatty acid amide hydrolase)IBA
10/2018
1nepicastatIBA
05/2018
1Pilocarpine (Ocusert)FDA LinkGeneric
01/2018
1LacosamideFDA Link
01/2018
1Catechol O-Methyltransferase InhibitorsIBA
12/2017
1FlagellinIBA
10/2017
1loxoribineIBA
10/2017
1LigandsIBA
10/2017
1Aromatic-L-Amino-Acid DecarboxylasesIBA
01/2017
1Neurotransmitter Agents (Neurotransmitter)IBA
04/2016
1ElectrolytesIBA
04/2016
1AminesIBA
04/2016
1PotassiumIBA
01/2016
1gamma-Aminobutyric Acid (GABA)IBA
10/2015
1Ethosuximide (Zarontin)FDA LinkGeneric
10/2015
1Antihypertensive Agents (Antihypertensives)IBA
01/2015
1Amino AcidsFDA Link
12/2014
1latrunculin A (LAT-A)IBA
12/2014

Therapy/Procedure

29Therapeutics
03/2022 - 12/2004
1Off-Label Use
10/2021
1Catheters
09/2015
1Oral Administration
12/2014
1Electrodes (Electrode)
02/2014
1Drug Therapy (Chemotherapy)
04/2013